ThreeLac Study - Nine Month Results

ThreeLac Study – Nine Month Results

This study was begun on October 1^st, 2004 and these are the results through June 30^th, 2005. It was conducted under the supervision of Miriam Jang, M.D. in San Rafael, California (17 patients), and John A. Green III, M.D. Head of the Evergreen Center in Oregon City, Oregon (1 patient), both of whom are DAN! doctors. None of the participants received anything of value other than ThreeLac. The patients will be followed up with at three month intervals for the next 15 months. The study was privately funded by a couple in Texas.

ThreeLac is a powder, dissolved on the tongue or mixed in a small amount of liquid and taken orally after a meal. Ingredients are: Bacillus Coagulans (200 million CFU), Bacillus Subtilis (25 million CFU), Group D, nontoxic strain of Enterococcus Faecalis (25 million CFU), Lemon Juice Powder, Refined Yeast Powder (feeds the live bacteria in storage and does not affect yeast sensitive individuals), and Fiber (FOS).

Study Protocol:

Dosage:

1-2 year olds: start at half packet; if no bad effects, then increase to 1 packet in 3 days time, then increase by half a packet every 3 or 4 weeks for a maximum of 3 packets per day.

3 years old and over: start at 1 packet and increase by half a pack as above.

For 11 years old and over, can increase up to 4 or 5 packets a day.

The guiding principle is that if nothing bad or good is happening (the child has reached a plateau), you can increase the dosage up to the maximum dosage.

Possible side effects:

The side effects are those of yeast die-off, which is mainly more “stimmy” or more irritability. If these side effects get to be bothersome, you can back off the dosage and hold it at that dosage until things improve. You can also give activated charcoal, 2 capsules, 2 or 3 times a day, between meals and supplements. Side effects usually would last a maximum 4-6 weeks during the yeast die-off period. The most important thing is to make sure that the patient is not constipated: increase Magnesium to the point of diarrhea and then ease back on it until diarrhea goes away. Additionally, Vitamin C may be added to increase movements. Glycerin suppositories may be given. BeneFiber or Fiber Choice may be given. It is simply imperative to keep the bowels moving.

Other supplements recommended:

Magnesium Malate and B-12, either sublingually or by shots.

Supplements to avoid:

Nystatin, Diflucan, Other Anti-Yeast medications or supplements, Caprylic Acid, Oil of Oregano, Grapefruit Seed Extract, Yeast Aid, Candidstatin, Uva, Ursi. Other probiotics are not necessary.

Foods to be avoided:

All casein: all dairy products, including yogurt, butter and cheese. All gluten products, including spelt. All sugars including honey, sorbitol, sucralose, syrups. Fruit juices to be kept to a minimum, a quarter dilution (one quarter juice to three parts water). Xylitol and Stevia are best for sweeteners. Chelation if heavy metals are present.

Patient Profiles:

Child #1: Initials A.K. Age: 5. Age at diagnosis: 2. Original diagnosis: Autism. Maximum number of ThreeLac packets taken per day: 4. Current number of packets taken per day: 1.

Child #2: Initials: S.Y. Age: 8.7. Age at diagnosis: 5. Original diagnosis: Autism. Maximum number of ThreeLac packets taken per day: 3. Current number of packets taken per day: 2.

Child #3: Initials: K.Y. Age: 11.5. Age at diagnosis: 8. Original diagnosis: Autism. Maximum number of ThreeLac packets taken per day: 3. Current number of packets taken per day: 2.

Child #4: Initials: D.F. Age: 3. Age at diagnosis: 15 months. Original diagnosis: Infantile Autism. Maximum number of ThreeLac packets taken per day: 3. Current number of packets taken per day: 2.

Child #5: Initials M.S. Age: 11. Age at diagnosis: 2. Original diagnosis: Autism. Maximum number of ThreeLac packets taken per day: 3. Current number of packets taken per day: 2.

Child #6: Initials: V.V. Age: 7. Age at diagnosis: 3.5. Original diagnosis: High functioning Autism. Maximum number of ThreeLac packets taken per day: 5. Current number of packets taken per day: 4.

Child #7: Initials: Z.M. Age: 4.2. Age at diagnosis: 21 months. Original diagnosis: ASD/PDD. Maximum number of ThreeLac packets taken per day: 6. Current number of packets taken per day: 4.

Child #8: Initials: J.B. Age: 5. Age at diagnosis: Not given. Original diagnosis: PDD-NOS. Maximum number of ThreeLac packets taken per day: 6. Current number of packets taken per day: 4.

Child #9: Initials: M.M. Age: 13.4. Age at diagnosis: 10. Original diagnosis: ADD, Asperger’s, Dyslexia, Dyspraxia. Maximum number of ThreeLac packets taken per day: 4. Current number of packets taken per day: 2.

Child #10: Initials: A.L. Age: 6.3 Age at diagnosis: 3.7 Original diagnosis: High-functioning Autism. Maximum number of ThreeLac packets taken per day: 4. Current number of packets taken per day: 4.

Child #11: Initials: A.R. Age: 4. Age at diagnosis: 20 months. Original diagnosis: Autism. Maximum number of ThreeLac packets taken per day: 5. Current number of packets taken per day: 1.

Child #12: Initials: R.S. Age: 3. Age at diagnosis: 2. Original diagnosis: Infantile Autism/Autism. Maximum number of ThreeLac packets taken per day: 4. Current number of packets taken per day: 4.

Child #13: Initials: Y.L. Age: 5.3. Age at diagnosis: 3.1. Original diagnosis: Moderate Autism. Maximum number of ThreeLac packets taken per day: 5. Current number of packets taken per day: 2.

Child #14: Initials: P.S. Age: 8.10. Age at diagnosis: 4. Original diagnosis: Autism – moderate to low functioning. Maximum number of ThreeLac packets taken per day: 2.5. Current number of packets taken per day: 2.

Child #15: Initials: J.D. Age: 4.5. Age at diagnosis: Not given. Original diagnosis: Autism. Maximum number of packets taken per day: Not given. Current number of packets taken per day: Not given. *

Child #16: Initials: J.L.1. Age: 4. Age at diagnosis: 2.4. Original diagnosis: “Straight” Autism (no retardation, ADD, PDD, etc.). Maximum number of ThreeLac packets taken per day: 3. Current number of packets taken per day: 3.

Child #17: Initials: J.L.2. Age: 3. Age at diagnosis: 2.2. Original diagnosis: “Straight Autism (no retardation, ADD, PDD, etc.). Maximum number of ThreeLac packets taken per day: 2. Current number of packets taken per day: 2.

Child #18: Initials: T.R. Age: 5. Age at diagnosis: 1.5. Original diagnosis: Autism. Maximum number of ThreeLac packets taken per day: 3. Current number of packets taken per day: 3.

At nine months, the percentage of improvement for each child is below (n/a means the symptom was not applicable for that child):

Child	#1	#2	#3	#4	#5	#6	#7	#8	#9	#10	#11	#12	#13	#14	#15	#16	#17	#18
Senses over-active	40	90	NA	NA	40	90	40	80	70	0	NA	NA	60	NA	30	60	NA	NA
Senses under-active	NA	90	NA	NA	60	NA	30	NA	70	20	NA	NA	NA	NA	30	NA	NA	NA
Over-reacts to being touched	NA	NA	NA	NA	90	60	50	80	70	NA	NA	NA	NA	NA	30	100	60	NA
Sensitivity to odors	NA	90	NA	NA	10	NA	NA	NA	70	NA	NA	NA	60	NA	NA	NA	NA	NA
Sensitivity to noise	NA	90	NA	60	90	40	50	70	70	20	NA	0	60	NA	30	40	NA	NA
Sensitivity to bright lights	NA	NA	NA	NA	90	NA	NA	NA	80	NA	NA	0	50	NA	20	40	NA	NA
Indifference to surroundings	40	NA	NA	90	70	NA	60	NA	70	NA	NA	NA	50	NA	50	NA	NA	60
Wants to always be alone	NA	90	NA	80	70	NA	50	NA	NA	NA	NA	NA	80	NA	40	100	NA	60
Lack of interest in toys	40	90	NA	80	80	30	50	80	40	NA	NA	NA	50	40	40	NA	NA	60
Lack of pointing to objects	60	70	NA	40	NA	NA	NA	80	0	10	NA	0	70	0	30	100	NA	60
Marked reduction in activity level	NA	80	NA	40	50	70	NA	80	80	NA	NA	NA	80	50	20	100	NA	60
Marked increase in activity level	50	NA	NA	60	40	30	30	NA	40	10	NA	60	NA	NA	20	NA	NA	60
Gross motor skills	50	80	NA	70	60	40	60	90	70	NA	NA	70	NA	NA	40	100	NA	60
Receptive language	60	NA	100	90	90	80	50	80	70	NA	50	70	60	30	30	100	100	60
Expressive language	50	NA	100	70	90	90	40	70	80	10	50	80	30	30	20	100	100	20
Tantrums	NA	NA	NA	50	90	NA	NA	90	60	10	NA	30	NA	60	10	0	0	NA
Aggressive behaviors	NA	NA	NA	NA	70	NA	NA	100	60	NA	NA	NA	NA	100	10	0	0	100
Distress level	NA	90	NA	60	70	40	NA	80	60	30	NA	40	50	100	20	20	0	NA
Repetitive speech	40	NA	NA	80	80	50	?	70	100	NA	NA	40	NA	NA	NA	NA	NA	NA
Repetitive physical motions	0	NA	NA	70	40	60	NA	80	90	NA	NA	NA	30	0	10	NA	NA	NA
Lack of interest in other people	40	80	NA	80	60	NA	50	80	80	20	NA	70	30	90	40	NA	NA	60
Resists changes in routine	NA	80	NA	90	90	30	60	80	70	NA	NA	NA	90	70	30	NA	NA	NA
Self-injurious behavior	NA	NA	NA	NA	NA	NA	NA	NA	70	NA	NA	NA	NA	NA	NA	NA	NA	100
Compulsive behaviors	NA	90	NA	20	60	30	NA	80	60	20	NA	NA	NA	NA	20	NA	NA	NA
Inappropriate attachment to objects	NA	90	NA	90	60	NA	NA	80	NA	NA	NA	0	70	NA	30	NA	NA	NA
Eye contact	40	80	NA	80	90	30	40	80	100	20	NA	70	90	70	30	NA	40	100
Over/under sensitivity to pain	40	80	NA	NA	70	NA	40	80	70	NA	NA	NA	50	NA	NA	NA	NA	NA
No fear of danger	NA	70	NA	NA	70	NA	30	60	NA	NA	NA	70	70	NA	20	NA	30	NA
Averages	42%	84%	100%	68%	68%	51%	46%	80%	69%	15%	50%	43%	59%	53%	27%	66%	41%	66%

(NA means a symptom was not applicable for that particular child) Additional Information: Chelation? How long/when & what kind? Also, list of other existing supplement routine prior to and during the study:

Out of 18 children, 12 (approximately 70%), got over 50% improvement, including 4 at 50%>, 5 at 60%>, 2 at 80%> and 1 at 100%. Four (22%) got 40%>, meaning approximately 92% got over 40% improvement, which is considered to be “clinically significant”. Only two children got less than 40% improvement.

Further improvements after the study concluded are shown below in the updates, including some reversals of diagnoses.

Child #1: Magnetic clay baths – ongoing. Other supplements: Daily Multi Vitamins, Dr. prescribed.

Child #2: Magnetic clay baths finished, transdermal DMPS – ongoing. Other supplements: H. Pheno, H Enzyme HN – Mult, H. Enzy – APF – gfcf, Zn monomethionine, Folic acid, Multicarotene, Co Q10, Black Currant, V E, Epson S cream, EFA, D Plex, B Complex, Eskimo oil, CLO flavored, Myelized A, PicMins, Custom amino acid base, LGS, 5-HTP, taurine, OPC – 100, Biotin-8, Sacro-B, L-carnitine. Parent's comments: "He likes to watch picture of books. His eye contact has improved. He sleeps 7-8 hours every day. He is gentle. He enjoys his life. He often smiles. So, we all enjoy peaceful life."

Update 11/11/2005: "Shoji enjoys his life. He does not speak yet. His stool is normal in toilet. He does not attack objects. He sleeps well about 9 hours. He likes to watch picture of books. He often smiles. Lack of pointing to objects is now 80% improved."

Child #3: No chelation listed. Other supplements: Carnosine, H. Pheno, H. Enzyme HN – Mult, H. Enzy – APF – gfcf, Zn monomethionine, Folic acid, Multi-Carotene, Co Q10, Black currant, V E, Epson S Cream, EFA, D Plex, B Complex, Eskimo oil, CLO, Myelized A, PicMins, Custom amino acid base, LGS, 5-HTP, taurine, OPC-100, Biotin – 8, L-Lysine. Parent's comments: "He can solve many questions of Science, Social Studies, Arithmetic, and Language. He likes to read Harry Potter. He is gentle."

Update 11/11/2005: "Kouichi studies hard. He will take the entrance examination of high school on Feb 1. His marks of mathematics, language, science and social subjects is steadily increasing. He wants to become a doctor. "

Child #4: TD-DMPS finished June 2005. Other supplements: Ambrotrose, Arabinex, Ascorbic acid, Amino acid, Biotin, Black currant oil, calcium Citramate, Carnosine, Cod liver oil, Co-Enzyme Q10, DMG + Flonic acid, D Plex, EFA, Enzymes – NF, ZP, AFP, Eskimo 3 fish oil, Glutathione cream, Glutathione liquid, 5-HTP Tryptophan, L-Arginine, L-Carnitine, L-Glutamine, L-Tyrosine, Magnesium sulfate, Mercurious Virus, Monolaurin, Multi-carotene, N-Acetyl Cysteine, OPC-100, Pantethine, Pic-Mins, Pyridoxal 5 phosphate, RNA – Nerve Calm, RNA – Health Foundation, RNA – Stress Foundation, RNA – Mood Focus, Sac. Boullardii, Selenium, Transfer Factor, Vitamin A, Vitamin B-12, Vitamin B Complex, Vitamin C, Vitamin E, Zinc, Zinc Sulphate.

Child #5: DMSA, Clay baths, TD-DMPS, still in progress. Other supplements: Super Nu Thera, Vitamin C, TMG/Folinic Acid/B12, CoQ10, Amino Acids, Methylcobalamin shot, Enzymes, Glutathione, Milk Thistle, Cod Liver oil, Monolaurin, Pro-Bio Gold, Hemp oil, EP oil, Multi Mineral, Transfer Factor, Zinc. Parent's comments: "Improved computer skills, improved handwriting and spelling. Has mastered tying shoes on shoe board."

Update 10/21/2005: "We have seen improvement in expressive speech. His Eczema on his arms is gone. He never gets sick anymore. His pain tolerance has improved. He will sit quietly thru meetings and conferences better than 3 months ago. He is helping us clean house and has a passion for it, for the first time I am starting to think he may be able to work!"

Child #6: DMPS finished, clay baths currently. Other supplements: Multi-vitamin, B6, DMG, folic acid, Glutathione, B-12 shots. Parent's comments: "Improvement of his fine motor skills. An increase in his sociability with other children. The most noticeable gain has been in the speech and cognitive areas. Although our son was verbal before, he has significantly narrowed his gap with the normally developing population over the past nine months."

Update 03-06-06: "V. continues to make good progress in new areas. The breakthroughs since the last report is that he now tolerates being kissed on the face, which is completely new! He is also noticeably calmer and less hypersensitive, which I credit the ThreeLac for. A recent stool test shows his candida burden at 2, which is better than the one we had six months ago. Overall, the child is maturing and doing fairly well. His language skills are stable.

Child #7: TD DMPS, ongoing. Other supplements: Lipoceutical Glutathione, Multi-vitamin, Multi-mineral, Buffered Vitamin C, Zinc, Transfer Factor, Amino Acid blend, L-Carnitine, Taurine, MB12 shots & Folinic Acid, Cod Liver oil. Parent's comments: "Toilet training improved (B.M.'s are the best)."

Update 11/11/2005: "today he was just amazing..yesterday for the first time in his life he sang a FULL song...usually he fills in blanks or makes me repeat each word after him... but he sang the entire ABC song pointing to the correct letters as he sang...not just once he did it so many times... he did it again today for 2 different people & he knows he' being cute coz he gives me a BIG hug when he's finished the song, so pleased with himself. Then to top that just an hour ago, he said "I want cookie"... NO PROMPT. Was able to take him off of Lipoceutical Glutathione, Transfer Factor, amino acid blend, L-Carnitine, Taurine, Folinic Acid and Cod Liver Oil."

Child #8: Magnetic Clay baths and Transdermal DMPS gel ongoing. Other supplements: Vitamin E w/Tocotrienols 400I.U., B-Complex #3 caps, Multi-Vitamin Pro-Support, Ascorbic Acid, Magnesium Malate, Zinc Monomethionine, Calcium Citramate, Pic-Mins (multi-minerals), Epsom Salt Cream, FlorVital Iron liquid, Cod Liver oil, CoQ10, BAM (Amino Acid base), L-Carnitine, Glycine, TMG w. Folinic acid & B12, L-Theanine, Melatonin, Sacro-B, O.P.C. (oligomeric Pranthocyanidin), Lipoceutical Glutithione, Methyl-B12 shots, Enzymes: No-Fenol, Zyme Prime, AFP Peptizyde. Parent's comments: "He is much better. Overall, a much calmer boy."

Child #9: Oral DMSA, two rounds only during study. Daily application of TTFD chelating cream. Other supplements: Essential fatty acids, Multi-vitamin, amino acids, Acetyl l-carnitine, Vitamin C, B6, Magnesium, Calcium, Vitamin E, Transfer Factors, Methylcobalamin injections, Glutathione lotion. Parent's comments: "She has improved well in areas of sociability and cognition. Sociability is 60% improved, irritability is 20% improved and academic is 60% improved."

Update 11/22/2005:"She has progressed wonderfully. If you met her now, it is unlikely you would know that she is autistic. She has made wonderful gains in the following areas: academics, sociability, gross and fine motor, sensory sensitivities, tantrums, aggression, receptive and expressive language, obsessive compulsive disorder, eye contact. The one area that has not normalized, and can sometimes be worse, is the area of anxiety. this is definitely related to the time of her periods, which only began this February, so it is early days yet. I am adjusting her intake of various nutrients such as magnesium, essential fatty acids and amino acids to see if that will help."

Child #10: Oral DMSA, 3/2005 – present. Other supplements: Pic-Mins, zinc monomethionine, selenium picolinate, magnesium malate, N-acetyl cysteine, L-carnitine, OPC-100, carnosine, taurine, multicarotene, CoQ10, glycine, biotin, folinic acid, Kirkman Nu Thera Everyday Companion, Kirkman EFA, amino acid mix, B-complex, vitamin A, vitamin B6 (P5P), vitamin C, vitamin E, black currant oil, fish oil, cod liver oil, glutathione, B-12 injections, T.A.P.S. (liver support), TTFD.

Child #11: DMPS transdermal prior to starting ThreeLac and ended in May, 2005, changing to clay baths. Other supplements: Micel A drops, Wellness LipoCeutical Glutathione, Black Elderberry extract, Cod liver oil, Eskimo oil, Transfer Factor, NAC, Multiple vitamin Pro Support, Magnesium malate, Selenium, Zinc monomethionine, Pic-Mins, ASD-Plex, Nu-Thera Everyday Companion, Amino acids, H. No-Fenol, H. HN-Zyme Prime Multi, H. Enzyme AFP Peptizyde cfgf, Kirkman vitamin C candies, Balanced Omega combination, Black currant oil, Hydrosoluble CoQ-10, Multi-carotene, Vitamin E, Taurine, L-Carnitine, O.P.C., Biotin-8, B-Complex #3, Folinic acid, Empsom salt cream, Zinc Sulfate cream, Methyl-B12 shot, Melatonin. Parent's comments: "She was off ThreeLac and all supplements completely for 8 weeks, and her diarrhea (of > 1yr) never returned. She also showed no regression and her behavior is that of a recovered autistic child (no behavioral symptoms). She is now able to tolerate moderate amounts of sugar, and we just started her on 1 packet/day maintenance and the rest of her supplements ½ dose. I think she's completely normal except for needing to stay on the diet and supplements. She still has a bit of a speech delay, but improved so much that it doesn't get in her way of making friends. She's one of the friendliest kids in her class. If you were to observe the class and guess which one is autistic, you probably wouldn't guess (my daughter). She's 90% potty trained."

Update 10/24/2004: "It's hard to say now how she's improved since she's a normal "recovered, indistinguishable" girl now (other than being unusually intelligent and friendly)."

Child #12: TD-DMPS ongoing. Other supplements: Custom amino acid, Carnosine, Buffered C, DMG w/ B-12 + folinic acid, Pic-Mins, OPC-100, Magnesium Malate, Transfer Factor, Co-Q10, LGS, Selenium Picolinate, Black Currant Oil, Folinic Acid, Sacro-B, Calcium Citramate, Vitamin E, B-Complex, Biotin-8, Zinc Monomethionine, Glycine, Micelized Vitamin A, Cod Liver Oil, Omega Brite, RNA, GABA, Pantethine, LipoCeutical Glutathione, TTFD cream, Glutathione cream, Epsom salts cream and baths. Parent's comments: "His imagination skills have improved. The ThreeLac has made a huge improvement with his stools. Mouthing has improved 100% and lining up objects has improved 50%."

Child #13: TD-DMPS since 12/6/2004, ongoing. Other supplements: Transfer Factor Advanced, Trace Mins, Pic Mins, Zinc Picolinate, Vit E with Tocotrienols, Evening Primrose oil, Black Currant, CoQ-10, Cod liver oil, Eskimo oil, Magnesium Malate, L-Tyrosine, D-Plex, Customized Amino Acids, Selenium, Biotin-8, B Complex #3, MB-12, Melatonin, 5HTP, GABA, Buffered C Powder, Calcium C, Taurine, Multi Vit Pro Support. Parent's comments: "Fine motor skills 50% improved. He is almost 100% toilet trained (90% improved)."

Child #14: DMPS finished Jan 2004. Other supplements: Enzyme Complete w/ DPPIV, melatonin, sulfasalazine, bethanecol, molybdenum, Amion Support, cellulose, cod liver oil, methyl B-12, folinic acid, calcium citrate. Parent's comments: "He is genuinely happy, playful, and totally interactive with us now. He feels good for the first time in years."

Child #15: No reply from parent regarding other questions after 30 days. May be on vacation.

Child #16: Clay baths – ongoing. Other supplements: AFP-Peptizyde, B-12 shot, Black Currant Oil, Carnosine, Cod Liver Oil, Custom Amino Acid Base, DMG w/Folinic Acid, D-Plex, EFA, Epsom S Cream, Eskimo-3 Oil, Hydrosoluble CoQ-10, L-Carnitine, L-Glutamine, Lipoceutical Glutathinoe, L-Methionine, Lycopene, Magnesium Malate, Micel-A, NAC N-Acetyl-Cysteine, No Fenol, Nu-Thera/Everyday Companion, Pantethine, Pic-Mins, Super Nu-Thera, Taurine, Vital-10, Vitamin E w/ Tocotrienols, Zinc, Zinc Monomethionine, Zyme Prime. Parent's comments: "He went from being mostly non-verbal to a "chatter box." He enjoys talking and singing. He has been diagnosed with apraxia of speech and as a result it's not always easy to understand what he's saying...but it's a huge improvement over where he was at when we started."

Update 9-12-06: "We are continuing with epsom salt cream and B-12 shots every night. We have cut back the supplements to multivitamins (like Super Nu-Thera) and the digestive enzymes. We continue to have both kids on the diet. J's progress has been amazing. He made several breakthroughs in the last few weeks. He can now pee standing up, he will poop in the toilet and he no longer needs a diaper at night (or any other time for that mater). He loves to talk and sing. He makes up his own words to tunes he's learned. He enjoys playing with his "Thomas" trains and has them carry on dialog with each other in the form of song - like a musical. He is an incredibly bright little kindergartner. He continues to get ABA and speech therapy and will soon be evaluated for OT due to some lingering sensory issues. Overall, though, we really couldn't be happier."

Child #17: Clay baths – ongoing. Other supplements: 5-HTP, AFP-Peptizyde, B-12 shot, B-Complex w/ CoEnzymes Pro, Black Currant Oil, Black Elderberry Extract, Cod Liver Oil, DMG w/ Folinic Acid, Epsom S Cream, Eskimo-2 Oil, Floradix, Glycine, Hydrosoluble CoQ-10, L-Carnitine, L-Glutamine, Lipoceutical Glutathione, L-Phenylalanine, Lycopene, Magnesium Malate, Melatonin, Micel-A, NAC N-Acetyl-Cysteine, No Fenol, Nu-Thera/Everyday Companion, O.P.C.-100, Pantethine, Pic-Mins, Super Nu-Thera, Taurine, Vital-10, Vitamin E w/ Tocotrienols, Zinc Monomethionine, Zyme Prime. Parent's comments: "She has always been a "chatter box." We have seen amazing changes in her as well. On her annual IQ tests she scored 39 points higher than last year... and 49 points on the other IQ test. If she was reevaluated today, the psychologist expects that she would lose her diagnosis."

Update 10/20/2005: "Her diagnosis has been officially reversed."

Child #18: Additional supplements: unknown. Parent's comments: "His visual awareness and performance is greatly improved along with eye contact. He now watches and learns from what he sees and now has spontaneous speech. He can now play and has social interaction. He can sit and participate in group instructions, follow classroom routines, generalize his responses and started reading, doing basic math and started learning the motions for writing. It was not uncommon before for T. to need 500 to 1,000 trials to learn something, and now he has learned things in 2 days, and more difficult things in 2 weeks. He can now count to 50 very easily and has gone up to 100. EVERYONE has noticed and commented on the changes in this child. T. now shows empathy and has run over to a child who was crying to hug him. He plays with his brother and will initiate the game. The stress has been reduced from our family - and has given us our family back. He has been pulled back out of the spinning world of autism. All of his self-mutilating behaviors have stopped. To sum it up - 6 months ago Tyler was doomed to live in an institution; he was withdrawn, had self mutilation behaviors and was nonverbal. Today we believe T will work (he loads and unloads the dishwasher now), be able to actively participate in life and love and succeed in whatever he wants to do. Last week T. said the sentence, "Momma, I love you!"

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Parents are continuing with ThreeLac and will over the course of the next several months bring their children to a maintenance dose of one or two packets per day. They were directed to the manufacturer's central US distributor in San Diego: https://www.globalhealthtrax.com/retail.